6 points, SCA Band 2, 0.125 EFTSL
Undergraduate - Unit
Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.
or or CHM2762. Students who have not completed and passed one of these units should consult the third year coordinator.
This unit focuses on several major classes of biologically and clinically important therapeutic agents. Students will study the traditional use, isolation, structural characterisation, synthesis and clinical evaluation of drugs and also be exposed to newer crystallographic, computational, combinatorial and screening methodology used in drug design and development. The subject will consist of three inter-related sections: a) drug discovery and development, b) molecular recognition, and c) chemistry and the synthesis of biological polymers. Where appropriate, guest speakers from industry and government agencies will contribute to the subject.
On completion of this unit students will be able to:
- Understand traditional and modern methods used for drug discovery;
- Understand how molecules interact at the molecular level and how this relates to the activity of drugs;
- Demonstrate how crystallography and computational methods are used for drug development;
- Demonstrate a knowledge of reaction mechanisms and how they can aid in understanding the mode of action of a drug;
- Demonstrate practical skills through the practice of chemical synthesis in a laboratory;
- Demonstrate the capacity to work in small research groups, to solve problems and communicate science in both written and oral forms.
Examination (2 hours): 40% (Hurdle)
Mid-semester test (40 mins): 20%
Laboratory work and short laboratory reports: 30% (Hurdle)
To pass this unit a student must achieve a minimum score of 50% in the laboratory practical component and a minimum of 30% for the end-of-semester exam.
Two 1-hour lectures/tutorials, one hour directed independent study and the equivalent of 3 hours of laboratory activity per week
See also Unit timetable information