Medicine Monash Health

Biography

Competitive research grants

2017: NHMRC/Cancer Australia Priority-driven Collaborative Cancer Research Scheme: Segelov E (CIA): Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers- An International, Multi-centre, Double Blind, Randomized Placebo Controlled Phase III Trial $600 000 over 3 years

2016-2021 National Medical Research Council, Singapore. CI Chia J; Segelov E as named international collaborator -$4.2M for ASCOLT Phase III randomised controlled trial.

2015 IMPACT Philanthropy Application Program, Perpetual Foundation. Segelov E  (CIA), Sieber O. Who benefits from aspirin? A translational study of samples collected on the international ASCOLT adjuvant colorectal cancer aspirin trial. $102,444 for 1 year.

2014-2018: NHMRC Project grant: Rogers M, Centre J, Phan TG, Jenner AM, Segelov E (CIE): How do bone-active drugs increase patient survival? Garvan Institute. $593 000 over 4 years

2014-2017: NHMRC/Cancer Australia Priority-driven Collaborative Cancer Research Scheme: SCOT: short course oncology treatment. Haydon A, Segelov E (CIB): $90,253 over 3 years.

2013-2016: NHMRC/Cancer Australia Priority-driven Collaborative Cancer Research Scheme: Segelov E (CIA): Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers- An International, Multi-centre, Double Blind, Randomized Placebo Controlled Phase III Trial $599 168 over 3 years

2014-2017: NMHRC: Personalised metastatic colorectal cancer medicine: accelerating clinical translation with collaborative meta-analyses based on individual-participant data. A/Prof Christos Karapetis, Associate Professor Michael Sorich, Professor Ross McKinnon, Associate Professor Marc Buyse (CIA); Segelov E (AI), Flinders University$291,601.25 over 3 years.

2011: NHMRC/Cancer Australia Priority-driven Collaborative Cancer Research Scheme: Haydon A, Segelov E:  Short Course Oncology Therapy - A study of adjuvant chemotherapy in colorectal cancer

2011: Health Workforce Australia grant: Preparation for workforce readiness: $50000

2009: Health Workforce Australia grant for integration of medical students in the preadmission clinic, St Vincent’s Private Hospital $100 000

2005: UNSW Learning and Teaching Award

2004: UNSW Equity Initiatives Grant: Medical Equity and Diversity Initiative

2002-3: UNSW Goldstar Maintenance award

2000-2: Bowel Cancer Foundation/South West Sydney Colorectal Tumour Group:

2000-3: South Western Sydney Clinical School postgraduate scholarship

Research grants - current applications

-NHMRC Project Grant: Seiber O, Segelov E (CIB) APP Personalisation of Aspirin Adjuvant Therapy in Patients with Dukes C and High Risk Dukes B Colorectal Cancer $1.4M

Industry grants awarded

2015-20 Principal Investigator for CommNETS: Five year award of seed funding from Ipsen Pty Ltd ($1.5 M).

2017 AGITG Preceptorship in Upper GI cancer - $60,000 p.a. awarded for 2017

2013-6 AGITG Preceptorship in Colorectal Cancer - $260,000 (ongoing; 4 years funding to date)

2015-6 ALTG Preceptorship in lung cancer- $120,000 p.a. (ongoing, 2 years funding to date)

2015-7 ANZUP Preceptorship in prostate cancer- - $180,000 p.a. (ongoing, 2 years funding to date )

2015 Principal Investigator for international study: CommNETS: A modified Delphi process to identify Gaps in International Neuroendocrine Tumour Research ($200,000: Ipsen Pty Ltd)

2011 Principal Investigator for international study ICECREAM: Irinotecan cetuximab response evaluation among patients with G13D mutation. Merck Serono $1.4 M.

 

Biography

Awards/Prizes

-2016 New Concept award, Australian Gastrointestinal Trials Group Annual Scientific Meeting

-Certificate of Outstanding Service, Clinical Oncological Society of Australia, 2010

-Vice Chancellors Award for Teaching Excellence, University of NSW, 2006

-Merck, Sharp and Dohme (Aust) Research Student Poster Award. PTEN Mutational Spectra and Expression Profile in Sporadic Microsatellite Stable and Unstable Colorectal Cancers. UNSW April, 2003 (Ph D student).

-NSW Cancer Council Travel Award for study in an overseas laboratory, 1996.

-AMRAD Young Investigator Award 1995. Awarded for oral presentation "Characteristics of novel cisplatin-sensitive cell lines" at 33rd Annual Scientific Meeting of the Australian Society for Medical Research, Melbourne 1995.

-MOG-Neupogen Travel Award 1994. Awarded for presentation at Keystone Conference on DNA repair, New Mexico, USA, March 1995.

-Burroughs Wellcome Prize for Pharmacology, Year III Medicine, University of Sydney, 1985.

 

International role

• European Society of Medical Oncology (ESMO) faculty member for the CUP, Endocrine Tumours and Others faculty group for the period 2017-2018.

• Member, Editorial Board of Journal Of Global Oncology (ASCO) 2015-

• Co-Founder, CommNETs: Commonwealth Neuroendocrine Tumour Society- an international research collaboration which I established in 2015 between Australia, Canada and New Zealand

• Track Chair, Gastrointestinal Cancer, ESMO Asia Annual Scientific Meeting 2017-

• International Chair, Short Course Oncology Treatment (SCOT Trial) Scientific Access Committee – oversight of use of tissue and blood samples (>5000) collected on the international SCOT trial

• International Head of Translational Studies for the ASCOLT Trial

• International Study Co-Chair for the ASCOLT Trial

• Member, Data Safety Monitoring Committee, TransTasman Radiation Oncology group 2015-

• Invited speaker at multiple international conferences

• Conference Convenor of:
o Australasian GastroIntestinal Trials Group Annual Scientific Meeting 2015-
o Commonwealth Neuroendocrine Tumour Society (CommNETS) Inaugural Meeting 2015-
o Clinical Oncology Society of Australia Annual Scientific Meeting 2008-11

• Conference Convening committee:
o COBRA: Controversies in Breast Cancer International Meeting 2015
o Organising Committee Member and Session Chair
• Medical Lead, Solomon Islands-St Vincent’s compassionate treatment program, 2007- 2016

• International grant reviewer: Cancer Research UK, National Medical Research Singapore

Editorial roles

-Editorial Board- invitation of Editor-in-Chief Professor David Kerr 2015- Journal of Global Oncology

-Board of Honorary Consultants, Medicine Today (by invitation) 2011- 2017

International clinical trial roles

Chair, Short Course Oncology Treatment Scientific Access Committee – oversight of use of tissue and blood samples (>5000) collected on the international SCOT trial

Member, Data Safety Monitoring Committee, TransTasman Radiation Oncology group 2015-

Clinical Lead (one of 4 International Principal Investigators, ASCOLT trial) and International Head of Translational Research for the ASCOLT study.

Founding member, International Adjuvant Aspirin Triallists Group

Chair, Clinical Trials Working Group, Commonwealth Neuroendocrine Tumour Collaboration

Research Grant Reviewer

-Cancer Research UK 2016-

-National Medical Research Council (NMRC) Singapore 2014-

-NHMRC project grants 2002-5, 2007, 2013, 2014, 2015, 2016

-NHMRC/Cancer Australia Priority-driven Collaborative Cancer Research Scheme 2014, 2015
-Cancer Society of New Zealand 2016-

-NHRMC Fellowship, 2012

-Clinical Oncological Society of Australia Grant awards committee 2010-

-Pfizer Young Investigator Cancer Research Grant 2011

-Pfizer Australia Cancer Grant reviewer 2009

-Carrick expert assessor, Institute Fellowship Scheme 2007           
              
-St Vincent’s Clinic Foundation grant reviewer 2005-7

-NSW Cancer Council project grants 2004

-South Western Sydney Health Research Foundation 2001-2


National/State Roles and Committees

Chair of Gastrointestinal Group and Council Member, Clinical Oncological Society of Australia 2010-

Board Member, Australian Gastro-Intestinal Trials Group (AGITG) 2014-

Member, Trans Tasman Radiation Oncology Group (TROG) Independent Data Safety Monitoring Committee (IDSMC)

Member, Medical and Scientific Committee of Cancer Council Victoria 2017-

Convenor, AGITG Annual Scientific Meeting 2015-

Convenor, Annual Scientific Meeting of COSA, 2008, 2009, 2010 and member of convening committee 2007, 2011.

Chair, Medical Oncology Subcommittee, AGITG Annual Scientific Meeting Convening Committee 2010-2014

Subcommittee member, Imaging and colorectal cancer, Clinical Guidelines Network, Cancer Council Australia 2016

Inaugural Co-Convenor, Advanced Trainee Education weekends prior to Annual Scientific Meeting of COSA, 2010-.

Convenor and Developer, AGITG Preceptorship in Colorectal Cancer, 2013-

Convenor and Developer, ALTG Preceptorship in Lung Cancer, 2015-

Convenor and Developer, ANZUP  Preceptorship in Genitourinary Cancer, 2015-

Advisory Board member, gestational breast cancer project, Australasian Maternity Outcomes Surveillance System (AMOSS)

Concept development and implementation co-author and member, steering committee: Australasian Tele‐Trial Model: Access to clinical trials closer to home using telehealth. Policy document, Clinical Oncology Society of Australia.

Member, Medical & Scientific Committee of Cancer Council Victoria 2017-


PROFESSIONAL MEMBERSHIPS (medical and scientific societies)

Member, American Society of Clinical Oncology (ASCO)

Member, European Society of Medical Oncology (ESMO)

Council Member and Chair of Gastrointestinal Cancer Group, Clinical Oncological Society of Australia (COSA)

Member, Medical Oncology Group of Australia (MOG)

Member, Australian Gastrointestinal Trials Group (AGITG) and CommNETS

Member, Australia New Zealand Breast Cancer Trials Group (ANZBCTG)

Member, Australian & New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP)

Member, Private Cancer Physicians of Australia (PCPA)


Manuscript and Book Reviews

Journal of Clinical Oncology

Gut

Gastroenterology

Asia-Pacific Journal of Clinical Oncology

International Journal of Cancer

Bone metastases and Molecular Mechanisms: Cancer Forum: 28(3), 2004

Molecular Genetics and Colorectal Neoplasia (2nd ed): Cancer Forum: 2005

Medical Journal of Australia

Australian Medical Student Journal

Community service

Community engagement

Medical service

Chief of diagnosis and oncology care, Compassionate Medical Program to Solomon Islands, St Vincent’s Hospital 2007-2016

Clinical reviewer, Cancer Cancer NSW Understanding Bowel Cancer booklet 2016

Board Service

Board Member, Australasian GastroIntestinal Trials Group 2015-

Speaking

Santa Sabina College “Maintaining Hope” guest speaker, Oct 2014

Invited Speaker, NSW Cancer Council Soiree 2011, 2013-5

Keynote speaker, Business Insights Forum, Commonwealth Bank of Australia Institutional & Business Banking Risk Management Nov 2012

Keynote address, Field of Women, St Vincent’s Hospital October 2012

Facilitator, panel discussion at consumer forum, Australian New Zealand Urological Prostate Trials Group, July 2012

Invited speaker, Garvan Institute Open Day 2011


Conference Convenor/organiser

2017-: GI track co-Chair (by invitation), ESMO Asia Annual Scientific Meeting

2015- Chair and Convenor, Commonwealth Neuroendocrine Tumour Meeting (COMMNETS), Hawaii November 2015 and Dec 2016

2016-2019 Convenor, AGITG Annual Scientific Meeting

2016 Convenor, 2nd ALTG National Preceptorship in Lung Cancer Oct 2016, Melbourne.

2016 Convenor, 2nd ANZUP National Preceptorship in Prostate Cancer Aug 2016, Sydney.

2016 Convenor, 4th AGITG National Preceptorship in Colorectal Cancer Nov 2016, Melbourne

2015 Member of organizing committee, CoBRA: Controversies in Breast Cancer International meeting, Melbourne, October

2015 Convenor, Inaugural ALTG National Preceptorship in Lung Cancer Apr 2015, Sydney.

2015 Convenor, Inaugural ANZUP National Preceptorship in Genitourinary Cancer Nov 2015, Sydney.

2015 Convenor, 3rd AGITG National Preceptorship in Colorectal Cancer Convenor and Preceptor, Dec 2015, Melbourne.

2014 Convenor, AGITG National Preceptorship in Colorectal Cancer Convenor and Preceptor, July 2014, Sydney.

2014 Convenor, 2nd AGITG National Preceptorship in Colorectal Cancer Convenor and Preceptor, July 2014, Sydney.

2014 Medical Oncology Chair, Convening committee for AGITG Annual Scientific Meeting, Brisbane

2013 Convenor, Inaugural AGITG National Preceptorship in Colorectal Cancer Convenor Aug 2013, Melbourne

2013 Medical Oncology Chair, Convening committee for AGITG Annual Scientific Meeting,

2012 Medical Oncology subcommittee member, Convening committee for AGITG Annual Scientific Meeting,

2011 Medical Oncology subcommittee member, Convening committee for AGITG Annual Scientific Meeting,

2010 Convenor, Clinical Oncological Society of Australia Annual Scientific Meeting (>1800 attendees)

2009 Convenor, Clinical Oncological Society of Australia Annual Scientific Meeting

2008 Convenor, Clinical Oncological Society of Australia Annual Scientific Meeting

Co-convenor Clinical Oncological Society of Australia Multidisciplinary Trainee Weekends prior to Annual Scientific Meeting 2011, 2012

ACTNOW NSW/ACT meeting 2010 (under auspices of Clinical Oncological Society of Australia)

Tailored Therapies Meeting, Focus on colorectal cancer, May 2012 (Chair of independent planning committee for industry meeting)

Chair, Medical Oncology Committee, AGITG ASM organising committee 2013-

Member of organizing committee, ANZ Association of Medical Educators, 2007.

COMMITTEE MEMBERSHIP AND CONTRIBUTIONS

Oncology related committees

Board member, Australian Gastrointestinal Trials Group (AGITG)
Chair, Gastrointestinal Cancer, and Council member, Clinical Oncological Society of Australia (COSA) 2010-
Co-Chair, ESMO Asia GI tract 2017-
Convenor, Annual Scientific Meeting of the AGITG 2015-
Convenor, Clinical Oncological Society of Australia (COSA) Annual Scientific Meeting 2008- 2010.
Member, NSW Cancer Institute eviQ cancer protocols committee
Convenor, “Everything you need to know about breast cancer” COSA Trainee weekend 2010
Convenor, Tailored Therapies in Colorectal Cancer National meeting, May 2012
Convenor, ACTNOW Oncology meeting, 2010
Scientific Advisory Committee member, Australian Gastrointestinal Trials Group 1999-
Member, Lower Gastrointestinal Cancer Working Group, Australian Gastrointestinal Trials Group 2011-
Committee member, NSW Cancer Institute- Standard Treatment Protocols (eviQ) 2004-
Board Member, NSW Cancer Survivors Centre.
Member, Centre for Rational Therapeutics, UNSW 2005-8

University of New South Wales
University committees
Member and Acting Chair, Human Research Ethics Committee UNSW 2004-7 
Faculty of Medicine representative, Gender Equity Advisory Committee UNSW 2008-9

Faculty of Medicine committees
Gender Equity and Diversity Committee 2010-
Member, Faculty of Medicine Promotions Committee for Senior Lecturer 2005-9
Member, Faculty of Medicine Conjoint Committee
Expert Working Party, Staff and Teaching 2005 (reports to Program Evaluation and Implementation Group):
• Co-author, Faculty of Medicine Teaching Workloads Discussion Paper
• Interviewer for applications to enroll in Medicine (as part of selection process) 2002-
• Senior Lecturer in Surgery selection committee, St Vincent’s Clinical School, 2005
• Associate Professor in Medicine selection committee, St Vincent’s Clinical School, 2008
• Clinical Medical Education Committee, Faculty of Medicine 2000-
• Chair, Skills Working Party
o Chair, subcommittee on Health Record Privacy legislation
Pre-Clinical Medical Education Committee, Faculty of Medicine 2000-5
Curriculum Development Committee 2006-2010
Common Campus Committee – Year 4 and 6 (Oncology Representative) 2000-
Examination committee- Years 3,4, 6, Faculty of Medicine 2000-2009
Rural Health Education Committee, Faculty of Medicine 2002-4
Transition Working Party 2004-5
Curriculum Development Committee 2008-10
Senior Years Committee 1999-2000 (foundation of New Medicine Program)
Clinical Learning and Assessment Committee, Faculty of Medicine 2004-9
 Chair, Phase 1 Trial examination committee
Phase 2 committee, Faculty of Medicine 2004-2011 
Independent Learning Project Committee 2005- 
Ageings and Endings Phase 1 design group 2004-

St Vincent’s Clinical School
Chair, Clinical Teaching Committee 2004-

South West Sydney Clinical School
Board of Medical Studies, South West Sydney Area Health Service 1999-2003
Clinical School Teaching Committee 1999-2003
Clinical Skills Centre Executive (Deputy Chair) 1999-2003

St Vincent’s and Mater Health Service

Vice Chair, Campus Medical Council 2004-9
St Vincent’s Hospital Medical Grand Rounds Committee 2004-8
General Clinical Training Committee for Interns and Residents 2004-
Inaugural Chair, Upper Gastrointestinal Cancer Tumour Board, St Vincents Hospital 2004-
Root cause analysis –subcommittee of Patient Safety and Quality Committee) 2005
Education Committee, St Vincent’s and Mater Health Service, 2006-

South Western Sydney Area Health Service

Medical Appointments Committee (multiple)
General Clinical Training Committee

Postgraduate medicine- learning and teaching roles
 
Supervisor, Advanced Trainee in Oncology, St Vincent’s Hospital 2005-
Supervisor, PGY1 and 2, Medical Oncology, St Vincent’s Hospital 2004-
Examiner, Royal Australasian College of Physicians, for FRACP Part 1 exam
Multiple presentations to postgraduate medical trainees, nursing trainees etc
Multiple presentations at Grand Rounds, Upper GI Tumour group Education sessions

Supervision interests

Student research supervision

Honours (UNSW Med): - Cosupervisor: C Lawley, S Liyanage
ILP (UNSW Med):
2016 (cosupervisor); Evani Hewa
2015 Nivanka da Silva (cosupervisor);
2009-14 T Scheinberg, J Meagher, T Lee, A Ballin, A Malik (cosupervisor);

Thesis reviews


-PhD University of Queensland – candidate 40348052, 2017
-Hons candidate, Uni Sydney, 2012
-PhD candidate, University of Sydney 2005
-BSc Hons candidate, UNSW, 2005
-BSc Hons candidate, UNSW, 2006 (Supervisor: Dr Megan Hitchens)
-Independent Learning Project assessor (multiple) 2008-

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