Aust Ctr for Blood Diseases


Ross is a laboratory head at the Australian Centre for Blood Diseases/Monash University. As a postdoctoral fellow in New York he helped develop RNA interference technology allowing the reversible inhibition of endogenous gene expression in cultured cells and transgenic mice. His laboratory now uses these techniques to investigate hematopoiesis and leukemia, focusing on genes recurrently mutated in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Of particular interest is understanding how recurrent mutations in hematopoietic transcription factors contribute to leukemogenesis, and novel strategies towards overcoming the differentiation block common to all acute leukemias.

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